Cost, implications, applications, dosage details, and additional information about Voranigo
Voranigo is a potent oral tablet used to treat some brain tumors. This medication contains the active ingredient vorasidenib.
Specifically, the Food and Drug Administration (FDA) has granted approval for Voranigo to treat grade 2 astrocytomas and oligodendrogliomas in both adults and children over 12 years old. This drug is prescribed for these brain tumors in specific situations. To learn more about the uses of Voranigo, dive into the "Voranigo uses" segment.
Medication insights:
- Medication Class: Voranigo falls under the category of isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor, classification of targeted cancer therapy.
- Availability: There's no generic version of Voranigo available yet, making it a brand-name only drug.
- Prescription: A prescription is required to obtain Voranigo, and it's deemed not a controlled substance.
Voranigo generic
As of now, Voranigo is only accessible as a branded medication and hasn't been released in its generic form.
A generic drug mirrors the active ingredient in a brand-name medication. Generics typically cost less than their brand-name counterparts.
Voranigo cost and coupons
The cost of Voranigo can differ based on your insurance plan, location, and pharmacy.
Financial aid and insurance assistance: For people who may require assistance in paying for Voranigo or guidance on insurance coverage, support is available.
Check out the ServierONE program for Voranigo. Reach out at 800-813-5905 or visit their website to find out if you meet the eligibility criteria for support such as a copay card.
Voranigo side effects
less than 40 kg (about 88 pounds [lb])
Voranigo may lead to minor or significant side effects. The following list showcases some of the key side effects linked to taking Voranigo, but they're not exhaustive.
For more information on potential side effects and suggestions for managing them, consult your doctor or pharmacist. They can provide advice tailored to your situation.
WARNING: After the Food and Drug Administration (FDA) authorizes a drug, they track and analyze side effects. Sharing your experience contributes to medication safety by providing doctors and researchers with more data on how the drug functions in real-life scenarios. If you experience any side effects while using Voranigo, consider reporting it to the FDA via MedWatch or by calling 800-FDA-1088.
20 mg once per day
Mild side effects:
- Fatigue
- Headache
- Nausea
- Diarrhea
- Constipation
- Decreased appetite
- Joint or muscle pain
- COVID-19
- Decreased white blood cell count
- Increased liver enzymes
Most of these side effects should alleviate within a few days to a couple of weeks. However, if they worsen or persist, discuss them with your doctor or pharmacist.
Serious side effects:
Severe side effects from Voranigo are comparatively rare, but they can occur. If you encounter serious side effects, contact your doctor immediately. Dial 911 or your local emergency number if your symptoms seem life-threatening or you believe you're experiencing a medical emergency.
Listed below are some serious side effects and their symptoms:
40 kg or more
- Liver problems, with potential symptoms including:
- Pain in the upper right abdomen
- Loss of appetite
- Severe tiredness or weakness
- Dark urine
- Jaundice
- Seizures, exhibiting symptoms such as:
- Staring into space
- Rapid blinking
- Sudden stiffening of arms and body
- Jerking body movements
- Loss of consciousness
ALLERGIC REACTIONVoranigo may trigger an allergic reaction. However, it wasn't reported in the drug's studies.
40 mg once per day
Voranigo uses
Voranigo for certain brain tumors
Voranigo is FDA-approved to treat certain brain tumors in adults and children over 12 years old, specifically grade 2 astrocytomas and oligodendrogliomas.
These tumors belong to a family of brain tumors known as gliomas. Astrocytomas begin in brain cells called astrocytes, while oligodendrogliomas originate in brain cells called oligodendrocytes.
Brain tumors are categorized based on their growth rate and rate of spreading, ranging from 1 (slow-growing) to 4 (fast-growing). Grade 2 brain tumors are classified as slow-growing tumors, although they can infiltrate nearby brain tissue.
Voranigo is intended for grade 2 astrocytomas and oligodendrogliomas with a specific genetic mutation (an abnormal alteration in a gene). Make sure to consult your doctor before starting Voranigo, as they may conduct a biopsy or other tests to determine if your tumor fits this criteria.
Common symptoms of grade 2 astrocytomas and oligodendrogliomas include:
- Headaches, especially worse in the morning
- Nausea and vomiting
- Vision, hearing, or speech problems
- Balance issues
- Weakness or numbness on one side of the body
- Changes in personality or behavior
- Seizures
Voranigo is a targeted cancer therapy aimed at preventing these brain tumors from increasing in size and worsening. Voranigo is typically prescribed after surgical treatment (biopsy or tumor removal) to inhibit tumor growth and progression.
Voranigo and children
Voranigo is FDA-approved for use in children over 12 years old to treat grade 2 astrocytomas and oligodendrogliomas.
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Voranigo hasn't been tested in children under 12 years old, so it's unknown whether the drug is safe or effective for this age group.
- Voranigo, a potent oral tablet, is primarily used to treat certain neurological conditions such as specific brain tumors like grade 2 astrocytomas and oligodendrogliomas, in both adults and children aged 12 and above.
- This drug is classified as an isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor, a type of targeted cancer therapy, according to its medication class.
- As of now, Voranigo is only available as a brand-name drug and does not have a generic alternative.
- Financial aid and insurance assistance are available for people having difficulty affording Voranigo or seeking guidance on insurance coverage.
- In addition to treating specific brain tumors, Voranigo might also be prescribed to manage other brain disorders and cancers as science and medical-conditions advance.
