Managing Kisqali-related Adverse Reactions
In the ongoing fight against breast cancer, Kisqali (ribociclib) has emerged as a significant treatment option for HR-positive, HER2-negative breast cancer. However, like many medications, Kisqali comes with a range of potential side effects.
One of the most important things to note is that Kisqali can affect heart rhythm, causing a condition known as QT prolongation. This can be detected through an electrocardiogram (EKG). Regular EKGs are recommended during long-term use of Kisqali to monitor this risk.
Another common side effect is the development of elevated liver enzymes, which could be a sign of more serious liver problems. Regular liver function tests are, therefore, essential before starting Kisqali and throughout treatment.
In addition, having abnormal electrolyte levels may increase the risk of heart problems as a side effect of Kisqali.
While weight gain is not likely with Kisqali, some patients may experience swelling (edema), which could lead to a small amount of weight gain.
Common, less severe side effects include diarrhea, nausea, fatigue, and infections. These side effects are manageable and can be alleviated through lifestyle changes such as drinking plenty of water, eating a well-balanced diet, and getting good quality sleep.
More serious side effects, though less common, include lung problems, serious skin reactions, low level of certain white blood cells, cardiac rhythm problems, liver problems, and allergic reactions. It's crucial to report any symptoms to your healthcare provider immediately.
It's worth noting that hair loss is among the more common side effects of Kisqali, occurring in 15% to 33% of people in clinical trials.
Kisqali belongs to a drug class called CDK4/6 inhibitors, a type of targeted cancer therapy. At present, there are no generic versions of Kisqali available.
In managing these side effects, regular monitoring of liver function tests, blood cell counts, and EKGs is recommended during long-term use. If elevated liver enzymes occur, the doctor may lower the Kisqali dosage or prescribe a different treatment.
In summary, while Kisqali offers a valuable treatment option for HR-positive, HER2-negative breast cancer, it's essential to be aware of its potential side effects and to maintain regular medical check-ups to manage these risks effectively.
- The science behind Kisqali's treatment for breast cancer also reveals potential side effects, such as heart rhythm issues (QT prolongation) detected through electrocardiograms (EKG) and liver function issues signified by elevated liver enzymes.
- In addition to these medical-conditions associated with Kisqali use, other less common, yet significant side effects include lung problems, serious skin reactions, low levels of certain white blood cells, cardiac rhythm problems, liver problems, and allergic reactions.
- Awareness and proactive management of these side effects play a critical role in the health-and-wellness of breast-cancer patients undergoing treatment with Kisqali, as regular monitoring of liver functions, blood cell counts, and EKGs can help identify and manage issues.
