Pemphigoid: Rare Autoimmune Skin Disease Focus of Research
Pemphigoid, a group of autoimmune skin diseases, is the focus of research by dermatologists and immunologists. Despite no specific doctor or researcher being found, the condition's pathogenesis and treatment are actively studied. It primarily affects the elderly and those with other autoimmune disorders, with a slight female prevalence.
Pemphigoid occurs when the immune system attacks healthy tissues, often without a clear trigger. Medications, radiation therapy, or ultraviolet light exposure may contribute in some cases. Diagnosis involves a dermatologist's examination, followed by a skin biopsy or blood test to confirm the presence of characteristic antibodies.
There are three main types of pemphigoid. Bullous pemphigoid, the most common, causes blistering on the arms, legs, and lower abdomen. Pemphigoid gestationis affects pregnant women or those who have recently given birth, with blisters typically forming on the arms, legs, and abdomen. Cicatricial pemphigoid, or mucous membrane pemphigoid, causes blistering on mucous membranes, mainly in the mouth and eyes.
Pemphigoid is a rare autoimmune disorder that can affect individuals of any age, including children and the elderly. Symptoms include blistering, hives, itching, and red rashes, with blisters being large, fluid-filled, and thick, and not rupturing easily. It causes skin rashes and blistering on the legs, arms, abdomen, and mucous membranes.