Prescription Drug Information: Glyxambi Formulations, Dosages, Usage Guidelines, and Additional Details
Glyxambi is a brand-name prescription medication that has been approved for adults with type 2 diabetes. This medication, which comes as a tablet, is intended for long-term treatment and is used to improve blood sugar levels in combination with diet and exercise.
Glyxambi contains two medications: empagliflozin and linagliptin. Empagliflozin belongs to a class of drugs known as sodium glucose cotransporter 2 inhibitors, while linagliptin is classified as a dipeptidyl peptidase-4 inhibitor.
Glyxambi comes in two strengths: 10-5 mg and 25-5 mg. It is typically taken once per day, usually in the morning, and can be taken with or without food.
Common side effects of Glyxambi include urinary tract infections, genital yeast infections, increased urination, nasopharyngitis (common cold symptoms), and upper respiratory tract infections. Patients may also experience increased thirst and symptoms related to changes in blood sugar levels such as those of low or high blood sugar.
Urinary tract infections and genital fungal infections are among the most frequently reported, likely related to empagliflozin’s mechanism of increasing glucose excretion through urine. Increased urination and thirst occur due to empagliflozin’s effect on kidney glucose handling. Nasopharyngitis and upper respiratory infections have also been reported.
Warning signs for serious infection or ketoacidosis include severe pain, fever, changes in urine color, and tenderness/swelling in the genital area. These require prompt medical care.
To help prevent infections while taking Glyxambi, patients should monitor their blood sugar and maintain good hygiene. It is also advisable to inform a healthcare provider about any kidney or liver issues before using this medication.
Patients are encouraged to use a medication reminder to help ensure they don't miss a dose. If you miss a dose of Glyxambi, take it as soon as you remember, but skip the missed dose if it's almost time for the next one.
If you have trouble opening medication bottles, ask your pharmacist about easy-open containers or tools that can make it easier. Some pharmacies offer labels with large print, braille, or a code to convert text to speech to aid those with visual impairments.
It is crucial to always follow the dosage prescribed by your doctor. At the moment, there is no generic form of Glyxambi available.
Lastly, it's important to note that Glyxambi is also used to reduce the risk of death in people with diabetes and cardiovascular disease.
[1] DrugBank Online. (2021). Empagliflozin. Retrieved from https://go.drugbank.com/drugs/DB11865 [2] Linagliptin. (2021). MedlinePlus. Retrieved from https://medlineplus.gov/druginfo/meds/a605012.html [3] Glyxambi. (2021). Mayo Clinic. Retrieved from https://www.mayoclinic.org/drugs-supplements/glyxambi-oral-route/description/drg-20070574 [5] Glyxambi. (2021). FDA Prescribing Information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/207382s036lbl.pdf
- Despite being a treatment for type 2 diabetes, Glyxambi also serves to reduce the risk of death in people with diabetes and cardiovascular disease.
- As Glyxambi isn't available in generic form, it's essential to always follow the dosage prescribed by your doctor.
- To prevent potential infections while on Glyxambi, patients should maintain good hygiene, monitor their blood sugar levels, and inform their healthcare provider about any kidney or liver issues before using this medication.
- Some chronic medical conditions, such as urinary tract infections and genital fungal infections, can be more common among patients taking Glyxambi, possibly due to the medication's mechanism of increasing glucose excretion through urine.
