Sweetener erythritol potentially endangers brain cells, according to a recent study - here's what you need to be aware of.
In recent studies, it has been discovered that the zero-calorie sweetener, erythritol, may pose a potential risk to human health, particularly in relation to stroke. The research, conducted using cultured human brain endothelial cells, indicates that long-term consumption of erythritol could increase the risk of stroke due to its adverse effects on blood vessel function and clot formation. However, definitive conclusions on long-term consumption and a safe upper limit are still pending.
Key findings from the research reveal several concerning effects when human brain microvascular endothelial cells were exposed to erythritol at concentrations found in typical sugar-free drinks. These include reduced nitric oxide production, increased endothelin-1, lowered production of tissue plasminogen activator (t-PA), and elevated reactive oxygen species (ROS). These changes can lead to constricted vessels and impaired clot breakdown, increasing the risk of stroke.
Additionally, erythritol has been shown to cause platelet clumping (aggregation) at doses as low as 30 grams – roughly the amount found in a pint of sugar-free ice cream. This could further promote clot formation.
While most studies have used single doses equivalent to one serving, the potential effects could be amplified with frequent, multiple servings per day. As of now, no established safe upper limit for erythritol consumption has been defined based on these new findings. Until more comprehensive human studies are conducted, experts recommend cautious consumption, especially among individuals with existing cardiovascular risk factors.
It is important to note that erythritol is a sugar alcohol that occurs naturally in fruits like grapes, and commercial erythritol is made by fermenting corn. Erythritol is nearly as sweet as sugar with a negligible effect on blood sugar, making it a popular ingredient in sugar-free and low-carb products.
While erythritol is generally considered safe by regulatory agencies, excessive intake in some people or over a prolonged period could pose risks. A new laboratory study also suggests that erythritol may damage cells lining the brain's blood vessels, raising valid concerns about long-term vascular health.
However, it is crucial to approach these findings with caution. While laboratory studies provide valuable insights, translating these findings to real-world effects requires careful consideration. The study tested only one dosage of erythritol under lab conditions, and more studies are needed to see if the observed effects hold up with repeated or long-term exposure, or in other types of cells.
In summary, emerging evidence suggests that frequent erythritol consumption might increase stroke risk through vascular and clotting dysfunction, but the precise risk magnitude and a safe intake threshold remain to be fully determined. Monitoring intake of erythritol-containing products is advisable while awaiting further research. For those with existing cardiovascular problems, moderating their intake of erythritol is recommended. More research is needed to understand the potential impact of erythritol on human health.
- While science continues to explore the health impacts of various substances, a recent study focused on workplace-wellness and medical-conditions, finding potential risks associated with the zero-calorie sweetener, erythritol.
- The research emphasized that long-term consumption of erythritol could increase the risk of respiratory-conditions like stroke, due to its adverse effects on blood vessel function and clot formation.
- Furthermore, the study revealed that erythritol causes skin-care concerns, as it has been shown to damage cells lining the brain's blood vessels, potentially impacting long-term vascular health.
- In light of these findings, experts suggest pursuing therapies-and-treatments, such as maintaining cardiovascular-health through balanced nutritional choices, weight-management, fitness-and-exercise, and proper skin-care.
- CBD, a compound known for its potential role in managing various medical-conditions, could also play a role in mitigating erythritol-related vascular risks, but further research is needed to confirm its effectiveness in this area.
- To ensure overall health-and-wellness and promote a well-rounded lifestyle, it's essential to keep track of erythritol consumption in products and consult with healthcare professionals for guidance on managing potential risks associated with frequent consumption.
